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INCENP Antikörper (AA 785-914)

INCENP Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6142441
  • Target Alle INCENP Antikörper anzeigen
    INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
    Bindungsspezifität
    • 7
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 785-914
    Reaktivität
    • 27
    • 11
    • 11
    • 1
    • 1
    • 1
    Human
    Wirt
    • 15
    • 12
    Kaninchen
    Klonalität
    • 15
    • 12
    Polyklonal
    Konjugat
    • 13
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser INCENP Antikörper ist unkonjugiert
    Applikation
    • 10
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequenz
    ALNVTVDVQS PACTSYQMTP QGHRAPPKIN PDNYGMDLNS DDSTDDEAHP RKPIPTWARG TPLSQAIIHQ YYHPPNLLEL FGTILPLDLE DIFKKSKPRY HKRTSSAVWN SPPLQGARVP SSLAYSLKKH
    Kreuzreaktivität
    Human, Ratte
    Produktmerkmale
    Polyclonal Antibodies
    Immunogen
    Recombinant fusion protein containing a sequence corresponding to amino acids 785-914 of human INCENP (NP_064623.2).
    Isotyp
    IgG
    Top Product
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  • Applikationshinweise
    WB,1:500 - 1:2000
    Kommentare

    HIGH QUALITY

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    INCENP (Inner Centromere Protein Antigens 135/155kDa (INCENP))
    Andere Bezeichnung
    INCENP (INCENP Produkte)
    Synonyme
    INCENP antikoerper, LOC572121 antikoerper, 2700067E22Rik antikoerper, AU019509 antikoerper, C130081E20 antikoerper, C77457 antikoerper, XL-INCENP antikoerper, incenp antikoerper, incenp-a antikoerper, incenp-b antikoerper, xINC antikoerper, xIncenp antikoerper, xl-incenp antikoerper, inner centromere protein antikoerper, inner centromere protein S homeolog antikoerper, inner centromere protein L homeolog antikoerper, INCENP antikoerper, Incenp antikoerper, incenp.S antikoerper, incenp antikoerper, incenp.L antikoerper
    Hintergrund
    In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and 'passenger,' or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term 'passenger proteins' encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis (Cutts et al., 1999 [PubMed 10369859]).[supplied by OMIM, Mar 2008],INCENP,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Cell Cycle,Centromere,INCENP
    Molekulargewicht
    104 kDa/105 kDa
    Gen-ID
    3619
    UniProt
    Q9NQS7
    Pathways
    Zellzyklus
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