GABARAPL2 Antikörper (AA 1-117)

Produktnummer ABIN6140880

Produktdetails anti-GABARAPL2 Antikörper

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Bindungsspezifität: AA 1-117

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABARAPL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MKWMFKEDHS LEHRCVESAK IRAKYPDRVP VIVEKVSGSQ IVDIDKRKYL VPSDITVAQF MWIIRKRIQL PSEKAIFLFV DKTVPQSSLT MGQLYEKEKD EDGFLYVAYS GENTFGF

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-117 of human GABARAPL2 (NP_009216.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GABARAPL2

Target: GABARAPL2 (GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2))

Andere Bezeichnung: GABARAPL2 (GABARAPL2 Produkte)

Synonyme: GABARAPL2 antikoerper, atg8 antikoerper, gef2 antikoerper, gate16 antikoerper, gate-16 antikoerper, Gef2 antikoerper, ATG8 antikoerper, ATG8C antikoerper, GATE-16 antikoerper, GATE16 antikoerper, GEF-2 antikoerper, GEF2 antikoerper, zgc:92319 antikoerper, 0610012F20Rik antikoerper, 2900019O08Rik antikoerper, AI173605 antikoerper, GABA type A receptor associated protein like 2 antikoerper, GABA(A) receptor-associated protein like 2 antikoerper, GABA(A) receptor-associated protein like 2 L homeolog antikoerper, gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2 antikoerper, GABARAPL2 antikoerper, gabarapl2 antikoerper, Gabarapl2 antikoerper, gabarapl2.L antikoerper

Hintergrund: Ubiquitin-like modifier involved in intra-Golgi traffic (By similarity. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation (By similarity. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity. Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.,GABARAPL2,ATG8,ATG8C,GATE-16,GATE16,GEF-2,GEF2,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Autophagy,Endocrine & Metabolism,Mitochondrial metabolism,Regulators,GABARAPL2

Molekulargewicht: 13 kDa

Gen-ID: 11345

UniProt: P60520

Pathways: Autophagie