FZD4 Antikörper (AA 37-222)

Produktnummer ABIN6140841

Produktdetails anti-FZD4 Antikörper

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Bindungsspezifität: AA 37-222

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FGDEEERRCD PIRISMCQNL GYNVTKMPNL VGHELQTDAE LQLTTFTPLI QYGCSSQLQF FLCSVYVPMC TEKINIPIGP CGGMCLSVKR RCEPVLKEFG FAWPESLNCS KFPPQNDHNH MCMEGPGDEE VPLPHKTPIQ PGEECHSVGT NSDQYIWVKR SLNCVLKCGY DAGLYSRSAK EFTDIW

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 37-222 of human FZD4 (NP_036325.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-FZD4 Antikörper (ABIN6140841)

Fu, Wang, Wan, Lin, Chang, Han: "Wnt5a mediated canonical Wnt signaling pathway activation in orthodontic tooth movement: possible role in the tension force-induced bone formation." in: Journal of molecular histology, Vol. 47, Issue 5, pp. 455-66, (2017) (PubMed).

Details zu FZD4

Target: FZD4 (Frizzled Family Receptor 4 (FZD4))

Andere Bezeichnung: FZD4 (FZD4 Produkte)

Synonyme: CG4626 antikoerper, DFz4 antikoerper, Dfz4 antikoerper, Dm Fz4 antikoerper, Dmel\\CG4626 antikoerper, Fz4 antikoerper, anon-WO0170980.10 antikoerper, anon-WO0170980.11 antikoerper, fz1 antikoerper, zg01 antikoerper, CD344 antikoerper, EVR1 antikoerper, FEVR antikoerper, FZD4S antikoerper, Fz-4 antikoerper, FzE4 antikoerper, GPCR antikoerper, hFz4 antikoerper, frizzled4 antikoerper, fz4 antikoerper, FZ-4 antikoerper, frizzled 4 antikoerper, frizzled class receptor 4 antikoerper, frizzled-4 antikoerper, frizzled class receptor 4 S homeolog antikoerper, fz4 antikoerper, fzd4 antikoerper, Tsp_10376 antikoerper, FZD4 antikoerper, Fzd4 antikoerper, fzd4.S antikoerper

Hintergrund: This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.,FZD4,CD344,EVR1,FEVR,FZD4S,Fz-4,Fz4,FzE4,GPCR,hFz4,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),mTOR Signaling Pathway,Cell Biology & Developmental Biology,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,CD markers,Stem Cells,FZD4

Molekulargewicht: 59 kDa

Gen-ID: 8322

UniProt: Q9ULV1

Pathways: WNT Signalweg, Hormone Transport, Sensory Perception of Sound