EIF4E2 Antikörper (AA 1-240)

Produktnummer ABIN6140086

Produktdetails anti-EIF4E2 Antikörper

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Bindungsspezifität: AA 1-240

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: MNNKFDALKD DDSGDHDQNE ENSTQKDGEK EKTERDKNQS SSKRKAVVPG PAEHPLQYNY TFWYSRRTPG RPTSSQSYEQ NIKQIGTFAS VEQFWRFYSH MVRPGDLTGH SDFHLFKEGI KPMWEDDANK NGGKWIIRLR KGLASRCWEN LILAMLGEQF MVGEEICGAV VSVRFQEDII SIWNKTASDQ ATTARIRDTL RRVLNLPPNT IMEYKTHTDS IKMPGRLGPQ RLLFQNLWKP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human EIF4E2 (NP_004837.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EIF4E2

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Andere Bezeichnung: EIF4E2 (EIF4E2 Produkte)

Synonyme: 4E-LP antikoerper, 4EHP antikoerper, EIF4EL3 antikoerper, IF4e antikoerper, Eif4el3 antikoerper, EIF4E2 antikoerper, id:ibd1007 antikoerper, zgc:110542 antikoerper, zgc:158544 antikoerper, MGC115622 antikoerper, 2700069E09Rik antikoerper, AI036339 antikoerper, AV129531 antikoerper, D0H0S6743E antikoerper, eukaryotic translation initiation factor 4E family member 2 antikoerper, eukaryotic translation initiation factor 4E member 2 antikoerper, eukaryotic translation initiation factor 4E family member 2 L homeolog antikoerper, EIF4E2 antikoerper, Eif4e2 antikoerper, eif4e2 antikoerper, eif4e2.L antikoerper

Hintergrund: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation. Acts as a repressor of translation initiation. In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3, suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity. In P-bodies, component of a complex that promotes miRNA-mediated translational repression.,EIF4E2,4E-LP,4EHP,EIF4EL3,IF4e,h4EHP,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,EIF4E2

Molekulargewicht: 27 kDa/28 kDa

Gen-ID: 9470

UniProt: O60573

Pathways: SARS-CoV-2 Protein Interaktom