EIF3L Antikörper (AA 1-230)

Produktnummer ABIN6140074

Produktdetails anti-EIF3L Antikörper

Target: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Bindungsspezifität: AA 1-230

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3L Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: MSYPADDYES EAAYDPYAYP SDYDMHTGDP KQDLAYERQY EQQTYQVIPE VIKNFIQYFH KTVSDLIDQK VYELQASRVS SDVIDQKVYE IQDIYENSWT KLTERFFKNT PWPEAEAIAP QVGNDAVFLI LYKELYYRHI YAKVSGGPSL EQRFESYYNY CNLFNYILNA DGPAPLELPN QWLWDIIDEF IYQFQSFSQY RCKTAKKSEE EIDFLRSNPK IWNVHSVLNV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human EIF3L (NP_057175.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:4000,IHC,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EIF3L

Target: EIF3L (Eukaryotic Translation Initiation Factor 3, Subunit L (EIF3L))

Andere Bezeichnung: EIF3L (EIF3L Produkte)

Synonyme: wu:fb66c05 antikoerper, zgc:64147 antikoerper, EIF3EIP antikoerper, EIF3S11 antikoerper, EIF3S6IP antikoerper, HSPC021 antikoerper, HSPC025 antikoerper, MSTP005 antikoerper, 0610011H21Rik antikoerper, D15N1e antikoerper, Eif3eip antikoerper, Eif3ip antikoerper, Eif3s6ip antikoerper, HSP-66Y antikoerper, PAF67 antikoerper, eif3eip antikoerper, eif3s6ip antikoerper, eukaryotic translation initiation factor 3, subunit 6 interacting protein antikoerper, eukaryotic translation initiation factor 3 subunit L antikoerper, eukaryotic translation initiation factor 3, subunit L antikoerper, eukaryotic translation initiation factor 3 subunit L L homeolog antikoerper, eif3s6ip antikoerper, EIF3L antikoerper, Eif3l antikoerper, eif3l.L antikoerper

Hintergrund: Component of the eukaryotic translation initiation factor 3 (eIF-3 complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC. The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression.,EIF3L,EIF3EIP,EIF3S11,EIF3S6IP,HSPC021,HSPC025,MSTP005,Epigenetics & Nuclear Signaling,EIF3L

Molekulargewicht: 61 kDa/66 kDa

Gen-ID: 51386

UniProt: Q9Y262

Pathways: Ribonucleoprotein Complex Subunit Organization