DAP3 Antikörper (AA 159-398)

Produktnummer ABIN6139399

Produktdetails anti-DAP3 Antikörper

Target: DAP3 (Death-Associated Protein 3 (DAP3))

Bindungsspezifität: AA 159-398

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: HLWVKNCRDL LQSSYNKQRF DQPLEASTWL KNFKTTNERF LNQIKVQEKY VWNKRESTEK GSPLGEVVEQ GITRVRNATD AVGIVLKELK RQSSLGMFHL LVAVDGINAL WGRTTLKRED KSPIAPEELA LVHNLRKMMK NDWHGGAIVS ALSQTGSLFK PRKAYLPQEL LGKEGFDALD PFIPILVSNY NPKEFESCIQ YYLENNWLQH EKAPTEEGKK ELLFLSNANP SLLERHCAYL

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 159-398 of human DAP3 (NP_387506.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DAP3

Target: DAP3 (Death-Associated Protein 3 (DAP3))

Andere Bezeichnung: DAP3 (DAP3 Produkte)

Synonyme: DAP-3 antikoerper, MRP-S29 antikoerper, MRPS29 antikoerper, bMRP-10 antikoerper, 4921514D13Rik antikoerper, im:6905684 antikoerper, death associated protein 3 antikoerper, DAP3 antikoerper, Dap3 antikoerper, dap3 antikoerper

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q.,DAP3,DAP-3,MRP-S29,MRPS29,bMRP-10,S29mt,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Mitochondrial translation,DAP3

Molekulargewicht: 41 kDa/45 kDa

Gen-ID: 7818

UniProt: P51398