CYP7A1 Antikörper (AA 20-280)

Produktnummer ABIN6139374

Produktdetails anti-CYP7A1 Antikörper

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Bindungsspezifität: AA 20-280

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP7A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: LILGIRRRQT GEPPLENGLI PYLGCALQFG ANPLEFLRAN QRKHGHVFTC KLMGKYVHFI TNPLSYHKVL CHGKYFDWKK FHFATSAKAF GHRSIDPMDG NTTENINDTF IKTLQGHALN SLTESMMENL QRIMRPPVSS NSKTAAWVTE GMYSFCYRVM FEAGYLTIFG RDLTRRDTQK AHILNNLDNF KQFDKVFPAL VAGLPIHMFR TAHNAREKLA ESLRHENLQK RESISELISL RMFLNDTLST FDDLEKAKTH L

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 20-280 of human CYP7A1 (NP_000771.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYP7A1

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Andere Bezeichnung: CYP7A1 (CYP7A1 Produkte)

Synonyme: CP7A antikoerper, CYP7 antikoerper, CYPVII antikoerper, CHAP antikoerper, CYP7S1 antikoerper, cyp7a1a antikoerper, zgc:63920 antikoerper, cytochrome P450 family 7 subfamily A member 1 antikoerper, cytochrome P450, family 7, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 7, subfamily A, polypeptide 1 antikoerper, cholesterol 7-alpha-hydroxylase antikoerper, CYP7A1 antikoerper, Cyp7a1 antikoerper, cyp7a1 antikoerper

Hintergrund: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body. Polymorphisms in the promoter of this gene are associated with defects in bile acid synthesis.,CYP7A1,CP7A,CYP7,CYPVII,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Cytochromes,Lipid Metabolism,Cholesterol Metabolism,Cytochromes,Lipases,Cardiovascular,Lipids,CYP7A1

Molekulargewicht: 57 kDa

Gen-ID: 1581

UniProt: P22680

Pathways: Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha