CYP7A1 Antikörper (C-Term)

Produktnummer ABIN392530

Produktdetails anti-CYP7A1 Antikörper

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Bindungsspezifität: AA 476-504, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYP7A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Homologie: Rb

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This CYP7A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 476-504 amino acids from the C-terminal region of human CYP7A1.

Klon: RB17086

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu CYP7A1

Target: CYP7A1 (Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))

Andere Bezeichnung: CYP7A1 (CYP7A1 Produkte)

Synonyme: CP7A antikoerper, CYP7 antikoerper, CYPVII antikoerper, CHAP antikoerper, CYP7S1 antikoerper, cyp7a1a antikoerper, zgc:63920 antikoerper, cytochrome P450 family 7 subfamily A member 1 antikoerper, cytochrome P450, family 7, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 7, subfamily A, polypeptide 1 antikoerper, cholesterol 7-alpha-hydroxylase antikoerper, CYP7A1 antikoerper, Cyp7a1 antikoerper, cyp7a1 antikoerper

Hintergrund: CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.

Molekulargewicht: 57661

Gen-ID: 1581

NCBI Accession: NP_000771

UniProt: P22680

Pathways: Steroid Hormone Biosynthesis, Carbohydrate Homeostasis, Regulation of Lipid Metabolism by PPARalpha