CHRNG Antikörper (AA 328-517)

Produktnummer ABIN6138600

Produktdetails anti-CHRNG Antikörper

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Bindungsspezifität: AA 328-517

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHRNG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NVSLRSPHTH SMARGVRKVF LRLLPQLLRM HVRPLAPAAV QDTQSRLQNG SSGWSITTGE EVALCLPRSE LLFQQWQRQG LVAAALEKLE KGPELGLSQF CGSLKQAAPA IQACVEACNL IACARHQQSH FDNGNEEWFL VGRVLDRVCF LAMLSLFICG TAGIFLMAHY NRVPALPFPG DPRPYLPSPD

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 328-517 of human CHRNG (NP_005190.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CHRNG

Target: CHRNG (Cholinergic Receptor, Nicotinic, gamma (CHRNG))

Andere Bezeichnung: CHRNG (CHRNG Produkte)

Synonyme: ACHRG antikoerper, Achr-3 antikoerper, Acrg antikoerper, cholinergic receptor nicotinic gamma subunit antikoerper, cholinergic receptor, nicotinic gamma L homeolog antikoerper, cholinergic receptor, nicotinic, gamma antikoerper, cholinergic receptor, nicotinic gamma antikoerper, cholinergic receptor, nicotinic, gamma polypeptide antikoerper, CHRNG antikoerper, chrng.L antikoerper, Chrng antikoerper, chrng antikoerper

Hintergrund: The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.,CHRNG,ACHRG,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRNG

Molekulargewicht: 52 kDa/57 kDa

Gen-ID: 1146

UniProt: P07510