B4GALT1 Antikörper (AA 50-215)

Produktnummer ABIN6137403

Produktdetails anti-B4GALT1 Antikörper

Target: B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))

Bindungsspezifität: AA 50-215

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser B4GALT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: LPQLVGVSTP LQGGSNSAAA IGQSSGELRT GGARPPPPLG ASSQPRPGGD SSPVVDSGPG PASNLTSVPV PHTTALSLPA CPEESPLLVG PMLIEFNMPV DLELVAKQNP NVKMGGRYAP RDCVSPHKVA IIIPFRNRQE HLKYWLYYLH PVLQRQQLDY GIYVIN

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-215 of human B4GALT1 (NP_001488.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu B4GALT1

Target: B4GALT1 (UDP-Gal:betaGlcNAc beta 1,4 Galactosyltransferase, Polypeptide 1 (B4GALT1))

Andere Bezeichnung: B4GALT1 (B4GALT1 Produkte)

Synonyme: B4GAL-T1 antikoerper, CDG2D antikoerper, GGTB2 antikoerper, GT1 antikoerper, GTB antikoerper, beta4Gal-T1 antikoerper, B-1,4-GalT antikoerper, B-1,4-GalT1 antikoerper, GalT antikoerper, Ggtb antikoerper, Ggtb2 antikoerper, b4Gal-T1 antikoerper, beta-1,4-GalT antikoerper, beta-1,4-GalT1 antikoerper, beta-1,4-galactosyltransferase 1 antikoerper, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 antikoerper, B4GALT1 antikoerper, B4galt1 antikoerper

Hintergrund: This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose <=> UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing. Two transcripts, which differ only at the 5' end, with approximate lengths of 4.1 kb and 3.9 kb encode the same protein. The longer transcript encodes the type II membrane-bound, trans-Golgi resident protein involved in glycoconjugate biosynthesis. The shorter transcript encodes a protein which is cleaved to form the soluble lactose synthase.,B4GALT1,B4GAL-T1,CDG2D,GGTB2,GT1,GTB,beta4Gal-T1,beta-1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Cardiovascular,Angiogenesis,B4GALT1

Molekulargewicht: 42 kDa/43 kDa

Gen-ID: 2683

UniProt: P15291

Pathways: Glycosaminoglycan Metabolic Process