ALAS1 Antikörper (AA 1-250)

Produktnummer ABIN6136754

Produktdetails anti-ALAS1 Antikörper

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Bindungsspezifität: AA 1-250

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALAS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MESVVRRCPF LSRVPQAFLQ KAGKSLLFYA QNCPKMMEVG AKPAPRALST AAVHYQQIKE TPPASEKDKT AKAKVQQTPD GSQQSPDGTQ LPSGHPLPAT SQGTASKCPF LAAQMNQRGS SVFCKASLEL QEDVQEMNAV RKEVAETSAG PSVVSVKTDG GDPSGLLKNF QDIMQKQRPE RVSHLLQDNL PKSVSTFQYD RFFEKKIDEK KNDHTYRVFK TVNRRAHIFP MADDYSDSLI TKKQVSVWCS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human ALAS1 (NP_954635.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ALAS1

Target: ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))

Andere Bezeichnung: ALAS1 (ALAS1 Produkte)

Synonyme: ALAS antikoerper, ALAS3 antikoerper, ALASH antikoerper, MIG4 antikoerper, ALAS-N antikoerper, Alas-1 antikoerper, Alas-h antikoerper, ALAS-H antikoerper, ALASN antikoerper, ALAS1 antikoerper, wu:fb58d01 antikoerper, wu:fi12g09 antikoerper, 5'-aminolevulinate synthase 1 antikoerper, aminolevulinic acid synthase 1 antikoerper, alanyl-tRNA synthetase protein antikoerper, aminolevulinate, delta-, synthase 1 antikoerper, ALAS1 antikoerper, Alas1 antikoerper, alas1 antikoerper, alas1.S antikoerper, alaS1 antikoerper

Hintergrund: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms.,ALAS1,ALAS,ALAS-H,ALAS3,ALASH,MIG4,Cancer,Signal Transduction,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial markers,Cardiovascular,Blood,ALAS1

Molekulargewicht: 12 kDa/70 kDa

Gen-ID: 211

UniProt: P13196

Pathways: Regulation of Lipid Metabolism by PPARalpha