ALAS1 Antikörper
Kurzübersicht für ALAS1 Antikörper (ABIN7265571)
Target
Alle ALAS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- ALAS1 Rabbit mAb
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Kreuzreaktivität
- Human
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Produktmerkmale
- Monoclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthesized peptide derived from human ALAS1
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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Andere Bezeichnung
- ALAS1
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Hintergrund
- This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],ALAS, ALAS-H, ALAS3, ALASH, MIG4,Blood,Cancer,Cardiovascular,Endocrine & Metabolism,Mitochondrial metabolism,Mitochondrial metabolism_Mitochondrial markers,Signal Transduction,ALAS1
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Molekulargewicht
- 71kDa
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Gen-ID
- 211
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UniProt
- P13196
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Pathways
- Regulation of Lipid Metabolism by PPARalpha
Target
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