Angiotensin II Type-1 Receptor Antikörper (AA 250-350)

Produktnummer ABIN6136653

Produktdetails anti-Angiotensin II Type-1 Receptor Antikörper

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Bindungsspezifität: AA 250-350

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Angiotensin II Type-1 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FFSWIPHQIF TFLDVLIQLG IIRDCRIADI VDTAMPITIC IAYFNNCLNP LFYGFLGKKF KRYFLQLLKY IPPKAKSHSN LSTKMSTLSY RPSDNVSSST K

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 250-350 of human AT1R/AGTR1 (NP_000676.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Angiotensin II Type-1 Receptor

Target: Angiotensin II Type-1 Receptor (AGTR1) (Angiotensin II Receptor, Type 1 (AGTR1))

Andere Bezeichnung: AGTR1 (AGTR1 Produkte)

Synonyme: AG2S antikoerper, AGTR1A antikoerper, AGTR1B antikoerper, AT1 antikoerper, AT1AR antikoerper, AT1B antikoerper, AT1BR antikoerper, AT1R antikoerper, AT2R1 antikoerper, AT2R1A antikoerper, AT2R1B antikoerper, HAT1R antikoerper, 1810074K20Rik antikoerper, AI551199 antikoerper, AT1a antikoerper, Agtr-1a antikoerper, Agtr1 antikoerper, Angtr-1a antikoerper, AT1A antikoerper, XAT-1 antikoerper, agtr1-A antikoerper, agtr1.2 antikoerper, AT1-R antikoerper, at1 antikoerper, AGTR1 antikoerper, Agtr-1b antikoerper, Angtr-1b antikoerper, agtr1 antikoerper, agtr1-a antikoerper, agtr1-b antikoerper, xAT antikoerper, angiotensin II receptor type 1 antikoerper, angiotensin II receptor, type 1a antikoerper, angiotensin II receptor type 1 S homeolog antikoerper, uncharacterized AGTR1 antikoerper, angiotensin II receptor, type 1b antikoerper, angiotensin II receptor type 1 L homeolog antikoerper, AGTR1 antikoerper, Agtr1a antikoerper, agtr1.S antikoerper, Agtr1 antikoerper, Agtr1b antikoerper, agtr1.L antikoerper

Hintergrund: Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed, however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.,AGTR1,AG2S,AGTR1B,AT1,AT1AR,AT1B,AT1BR,AT1R,AT2R1,HAT1R,Cancer,Invasion and Metastasis,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Cardiovascular,Angiogenesis,Angiogenic growth factors,Blood,Blood Pressure regulation,AGTR1

Molekulargewicht: 41 kDa

Gen-ID: 185

UniProt: P30556

Pathways: JAK-STAT Signalweg, ACE Inhibitor Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour