Activin A Receptor Type IB/ALK-4 Antikörper (AA 24-126)

Produktnummer ABIN6221109

Produktdetails anti-Activin A Receptor Type IB/ALK-4 Antikörper

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Bindungsspezifität: AA 24-126

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Activin A Receptor Type IB/ALK-4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SGPRGVQALL CACTSCLQAN YTCETDGACM VSIFNLDGME HHVRTCIPKV ELVPAGKPFY CLSSEDLRNT HCCYTDYCNR IDLRVPSGHL KEPEHPSMWG PVE

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-126 of human ACVR1B (NP_004293.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Activin A Receptor Type IB/ALK-4 Antikörper (ABIN6221109)

Dong, Liu, Meng, Liu, Bi, Wu, Jin, Yao, Tang, Wang, Li, Zhang, Yu, Zhan, Chen, Ge, Yang, Li: "Keratin 8 limits TLR-triggered inflammatory responses through inhibiting TRAF6 polyubiquitination." in: Scientific reports, Vol. 6, pp. 32710, (2018) (PubMed).

Details zu Activin A Receptor Type IB/ALK-4

Target: Activin A Receptor Type IB/ALK-4 (ACVR1B) (Activin A Receptor, Type IB (ACVR1B))

Andere Bezeichnung: ACVR1B (ACVR1B Produkte)

Synonyme: ACVR1B antikoerper, alk4 antikoerper, skr2 antikoerper, alk-4 antikoerper, xalk4 antikoerper, actrib antikoerper, acvrlk4 antikoerper, DKFZp469A1614 antikoerper, 6820432J04 antikoerper, ActR-IB antikoerper, ActRIB antikoerper, Acvrlk4 antikoerper, Alk4 antikoerper, SKR2 antikoerper, ACTRIB antikoerper, ACVRLK4 antikoerper, ALK4 antikoerper, Skr2 antikoerper, axis antikoerper, taram-a antikoerper, tarama antikoerper, wu:fb75f01 antikoerper, activin A receptor type 1B antikoerper, Activin receptor type-1B antikoerper, activin A receptor, type IB antikoerper, activin A receptor, type 1B antikoerper, activin A receptor type 1Ba antikoerper, ACVR1B antikoerper, acvr1b antikoerper, acv1b antikoerper, Acvr1b antikoerper, acvr1ba antikoerper

Hintergrund: This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.,ACVR1B,ACTRIB,ACVRLK4,ALK4,SKR2,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Microfilaments,Stem Cells,ACVR1B

Molekulargewicht: 51 kDa/53 kDa/54 kDa/56 kDa/61 kDa

Gen-ID: 91

UniProt: P36896