Activin A Receptor Type IB Antikörper (Activin A Receptor, Type IB) (AA 39-68)

Details for Product anti-ACVR1B Antibody No. ABIN392231, Anbieter: Anmelden zum Anzeigen
Antigen
  • ACVR1B
  • alk4
  • skr2
  • alk-4
  • xalk4
  • actrib
  • acvrlk4
  • DKFZp469A1614
  • 6820432J04
  • ActR-IB
  • ActRIB
  • Acvrlk4
  • Alk4
  • SKR2
  • ACTRIB
  • ACVRLK4
  • ALK4
  • Skr2
  • axis
  • taram-a
  • tarama
  • wu:fb75f01
  • activin A receptor type 1B
  • Activin receptor type-1B
  • activin A receptor, type IB
  • activin A receptor, type 1B
  • activin A receptor type 1Ba
  • ACVR1B
  • acvr1b
  • acv1b
  • Acvr1b
  • acvr1ba
Epitop
AA 39-68, N-Term
21
15
11
11
9
9
6
6
5
4
3
3
2
2
2
1
1
1
1
1
Reaktivität
Human, Maus
134
86
38
1
Wirt
Kaninchen
106
41
6
2
Klonalität (Klon)
Polyklonal ()
Konjugat
Dieser Activin A Receptor Type IB Antikörper ist unkonjugiert
15
7
5
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS), Western Blotting (WB)
123
75
28
26
13
12
8
6
4
4
3
2
2
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen This Activin A Receptor Type IB (ACVR1B) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 AA from the N-terminal region of human Activin A Receptor Type IB (ACVR1B).
Klon RB3740
Isotyp Ig Fraction
Spezifität This ACVR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47~76 amino acids from the N-terminal region of human ACVR1B.
Homologie Rat (Rattus)
Reinigung This antibody is purified through a protein A column, followed by peptide affinity purification.
Plasmids, Primers & others Plasmide, Primers & weitere Activin A Receptor Type IB products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Activin A Receptor Type IB (ACVR1B) (ACVR1B Antibody Abstract)
Hintergrund Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with a cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. The gene for ACVR1B (activin A type IB receptor) is composed of 11 exons. Alternative splicing and alternative polyadenylation result in 3 fully described transcript variants. The mRNA expression of variants 1, 2, and 3 is confirmed, and a potential fourth variant contains an alternative exon 8 and lacks exons 9 through 11, but its mRNA expression has not been confirmed.
Synonyms: Serine/threonine-protein kinase receptor R2, SKR2, Activin receptor-like kinase 4, ALK-4, ACTR-IB
Molekulargewicht 56806 DA
Gen-ID 91
UniProt P36896
Applikations-hinweise WB = 1:1000, FACS = 1:10-50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit 6 months
Bilder des Herstellers
Western Blotting (WB) image for anti-Activin A Receptor, Type IB (ACVR1B) (AA 39-68), (N-Term) antibody (ABIN392231) The anti-ACVR1B Pab (ABIN392231) is used in Western blot to detect ACVR1B in mouse ki...
Flow Cytometry (FACS) image for anti-Activin A Receptor, Type IB (ACVR1B) (AA 39-68), (N-Term) antibody (ABIN392231) Flow cytometric analysis of 293 cells using Activin A Receptor Type IB (ACVR1B) Antib...
Western Blotting (WB) image for anti-Activin A Receptor, Type IB (ACVR1B) (AA 39-68), (N-Term) antibody (ABIN392231) Anti-Activin A Receptor Type IB (ACVR1B) Antibody (N-term) at 1:1000 dilution + Human...
Western Blotting (WB) image for anti-Activin A Receptor, Type IB (ACVR1B) (AA 39-68), (N-Term) antibody (ABIN392231) All lanes : Anti-Activin A Receptor Type IB (ACVR1B) Antibody (N-term) at 1:1000 dilu...
Western Blotting (WB) image for anti-Activin A Receptor, Type IB (ACVR1B) (AA 39-68), (N-Term) antibody (ABIN392231) All lanes : Anti-Activin A Receptor Type IB (ACVR1B) Antibody (N-term) at 1:1000 dilu...
Allgemeine Veröffentlichungen Harrison, Gray, Koerber, Fischer, Vale: "Identification of a functional binding site for activin on the type I receptor ALK4." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 21129-35, 2003 (PubMed).

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