ABCA1 Antikörper (AA 1870-2120)

Produktnummer ABIN6136332

Produktdetails anti-ABCA1 Antikörper

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Bindungsspezifität: AA 1870-2120

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ABCA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: IQYRFFIRPR PVNAKLSPLN DEDEDVRRER QRILDGGGQN DILEIKELTK IYRRKRKPAV DRICVGIPPG ECFGLLGVNG AGKSSTFKML TGDTTVTRGD AFLNKNSILS NIHEVHQNMG YCPQFDAITE LLTGREHVEF FALLRGVPEK EVGKVGEWAI RKLGLVKYGE KYAGNYSGGN KRKLSTAMAL IGGPPVVFLD EPTTGMDPKA RRFLWNCALS VVKEGRSVVL TSHSMEECEA LCTRMAIMVN G

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1870-2120 of human ABCA1 (NP_005493.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-ABCA1 Antikörper (ABIN6136332)

Qian, Ma, Wu, Yu, Lin, Ying, Wen, Gao: "G004, a synthetic sulfonylurea compound, exerts anti-atherosclerosis effects by targeting SIRT1 in ApoE-/- mice." in: Vascular pharmacology, Vol. 89, pp. 49-57, (2017) (PubMed).

Details zu ABCA1

Target: ABCA1 (ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1))

Andere Bezeichnung: ABCA1 (ABCA1 Produkte)

Synonyme: ABC-1 antikoerper, ABC1 antikoerper, CERP antikoerper, HDLDT1 antikoerper, TGD antikoerper, ABCA1 antikoerper, Abc1 antikoerper, ATP-binding cassette A1 antikoerper, Arabidopsis thaliana ATP-binding cassette A1 antikoerper, AtABCA1 antikoerper, im:7136239 antikoerper, sb:cb407 antikoerper, wu:fa07e06 antikoerper, zgc:171581 antikoerper, ATP binding cassette subfamily A member 1 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 1 antikoerper, ATP-binding cassette A1 antikoerper, ATP-binding cassette, sub-family A (ABC1), member 1B antikoerper, ABCA1 antikoerper, Abca1 antikoerper, abca1 antikoerper, abca1b antikoerper

Hintergrund: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.,ABCA1,ABC-1,ABC1,CERP,HDLDT1,TGD,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Neuroscience,Cell Type Marker,Cardiovascular,Heart,Lipids,Cardiovascular diseases,Heart disease,Astrocyte marker,ABCA1

Molekulargewicht: 254 kDa

Gen-ID: 19

UniProt: O95477

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism