IL17RC Antikörper

Produktnummer ABIN5957059

Produktdetails anti-IL17RC Antikörper

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17RC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: IL 17 receptor C,IL 17RC,IL 17RL,IL17 receptor C,IL17F receptor,IL17RL,Interleukin 17 receptor C,Interleukin 17 receptor homolog,Interleukin 17 receptor like,Interleukin 17 receptor like protein

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human IL-17RC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IL17RC

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Andere Bezeichnung: IL-17RC (IL17RC Produkte)

Synonyme: IL17-RL antikoerper, IL17RL antikoerper, 1110025H02Rik antikoerper, Gm19850 antikoerper, IL-17RC antikoerper, IL17-RC antikoerper, Il17rl antikoerper, interleukin 17 receptor C antikoerper, Il17rc antikoerper, IL17RC antikoerper

Hintergrund: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

Molekulargewicht: 86kDa

Gen-ID: 84818

UniProt: Q8NAC3