IL17RC Antikörper

Produktnummer ABIN7000063

Produktdetails anti-IL17RC Antikörper

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL17RC Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktmerkmale: Polyclonal Antibody

Aufreinigung: Affinity purification

Immunogen: Recombinant protein of human IL17RC

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC 1:25-1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu IL17RC

Target: IL17RC (Interleukin 17 Receptor C (IL17RC))

Andere Bezeichnung: IL17RC (IL17RC Produkte)

Synonyme: IL17-RL antikoerper, IL17RL antikoerper, 1110025H02Rik antikoerper, Gm19850 antikoerper, IL-17RC antikoerper, IL17-RC antikoerper, Il17rl antikoerper, interleukin 17 receptor C antikoerper, Il17rc antikoerper, IL17RC antikoerper

Hintergrund: This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

UniProt: Q8NAC3