C5 Antikörper

Produktnummer ABIN576124

Produktdetails anti-C5 Antikörper

Target: C5 (Complement Component 5 (C5))

Reaktivität: Human

Wirt: Schaf

Klonalität: Polyklonal

Konjugat: Dieser C5 Antikörper ist unkonjugiert

Applikation: Immunodiffusion (ID)

Spezifität: Recognizes complement component 5 (C5), a member of the complement system. The complement system consists of a tightly regulated network of proteins. Its activation leads to a sequential cascade of enzymatic reactions, resulting in opsonisation of the pathogens and their removal by phagocytes, as well as cell lysis. Three pathways have been described, the antibody-dependent pathway (classical pathway), the alternative pathway and the lectin activation pathway. The complement system plays a critical role in both innate and adaptive immune responses. It is also involved in tissue regeneration, tumor growth and some human pathologies. Complement component 5 is the initiator of the effector terminal phase of the complement system. C5 convertase cleaves C5 into C5a, a potent anaphylatoxin, and C5b, ultimately resulting in the formation of the multimeric membrane attack complex (MAC) together with the other components of the terminal pathway (C5b-C9). Gives a single arc when tested by immunoelectrophoresis (IEP) against human plasma. The identity has been confirmed by double diffusion against fresh human plasma and a known anti human C5.

Aufreinigung: Ion exchange chromatography

Immunogen: Human C5, purified from plasma.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Glycine buffered saline,  pH 7.4, 0.09 % sodium azide, 0.1 % EACA, 0.01 % benzamidine, 1 mM EDTA.

Konservierungsmittel: Sodium azide, Benzamidine, EACA

Vorsichtsmaßnahmen: This product contains Benzamidine and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Details zu C5

Target: C5 (Complement Component 5 (C5))

Andere Bezeichnung: Complement C5 (C5 Produkte)

Synonyme: C5 antikoerper, LOC565774 antikoerper, C5a antikoerper, C5b antikoerper, CPAMD4 antikoerper, Hc antikoerper, RGD1561905 antikoerper, He antikoerper, complement C5 antikoerper, complement component 5 antikoerper, hemolytic complement antikoerper, C5 antikoerper, c5 antikoerper, Hc antikoerper

Hintergrund: Name/Gene ID: C5

Synonyms: C5, Anaphylatoxin C5a analog, CPAMD4, Complement C5, Complement component 5

Gen-ID: 727

UniProt: P01031

Pathways: Komplementsystem, Carbohydrate Homeostasis