ICOS Antikörper (AA 57-71)

Produktnummer ABIN574320

Produktdetails anti-ICOS Antikörper

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Bindungsspezifität: AA 57-71

Reaktivität: Human, Affe

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser ICOS Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human ICOS.

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%) Marmoset, Pig (87%) Elephant (80%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide KGGQILCDLTKTKGS from an internal region of human ICOS (NP_036224.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%), Marmoset, Pig (87%), Elephant (80%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:32000)

Usage: Western Blot: Preliminary experiments gave an approx 13kD band in Human Peripheral Blood Lymphocyte lysates after 0.01 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 22.6kD according to NP_036224.1. The 13kD band was successfully blocked by incubation with the immunizing peptide. Have any further splice variants/modified forms been reported?

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Andere Bezeichnung: ICOS / CD278 (ICOS Produkte)

Synonyme: ICOS antikoerper, AILIM antikoerper, CCLP antikoerper, CRP-1 antikoerper, H4 antikoerper, Ly115 antikoerper, CD278 antikoerper, CVID1 antikoerper, Ailim antikoerper, inducible T-cell costimulator antikoerper, inducible T cell co-stimulator antikoerper, inducible T-cell co-stimulator antikoerper, ICOS antikoerper, LOC100232284 antikoerper, Icos antikoerper

Hintergrund: Name/Gene ID: ICOS

Synonyms: ICOS, AILIM, CD278, CVID1, Inducible costimulator, Inducible T-cell co-stimulator, CD278 antigen, Inducible T-cell costimulator

Gen-ID: 29851

NCBI Accession: NP_036224

UniProt: Q9Y6W8

Pathways: Cancer Immune Checkpoints