CBX3 Antikörper

Produktnummer ABIN5708343

Produktdetails anti-CBX3 Antikörper

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids A2-Q183 was used as the immunogen for the CBX3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CBX3 antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CBX3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu CBX3

Target: CBX3 (Chromobox Homolog 3 (CBX3))

Andere Bezeichnung: HP1 gamma / Heterochromatin protein-1 gamma / CBX3 (CBX3 Produkte)

Synonyme: HECH antikoerper, HP1-GAMMA antikoerper, HP1Hs-gamma antikoerper, Hp1-gamma antikoerper, HP1g antikoerper, M32 antikoerper, cbx3 antikoerper, cbx3a antikoerper, xhp1g antikoerper, wu:fb61b02 antikoerper, zgc:153397 antikoerper, chromobox 3 antikoerper, chromobox 3 L homeolog antikoerper, chromobox protein homolog 3 pseudogene antikoerper, chromobox homolog 3a (HP1 gamma homolog, Drosophila) antikoerper, CBX3 antikoerper, Cbx3 antikoerper, cbx3.L antikoerper, LOC100355282 antikoerper, cbx3a antikoerper

Hintergrund: Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.

UniProt: Q13185