ERCC6 Antikörper (AA 160-205)

Produktnummer ABIN5708072

Produktdetails anti-ERCC6 Antikörper

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Bindungsspezifität: AA 160-205

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERCC6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Antigen affinity purified

Immunogen: Amino acids 160-205 (QAATSRDINRKLDSVKRQKYNKEQQLKKITAKQKHLQAILGGAEVK) from the human protein were used as the immunogen for the CSB antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the CSB antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu ERCC6

Target: ERCC6 (Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 6 (ERCC6))

Andere Bezeichnung: Cockayne Syndrome B (ERCC6 Produkte)

Synonyme: ARMD5 antikoerper, CKN2 antikoerper, COFS antikoerper, COFS1 antikoerper, CSB antikoerper, RAD26 antikoerper, UVSS1 antikoerper, 4732403I04 antikoerper, C130058G22Rik antikoerper, ercc6 antikoerper, Ercc6 antikoerper, ERCC excision repair 6, chromatin remodeling factor antikoerper, excision repair cross-complementing rodent repair deficiency, complementation group 6 antikoerper, excision repair cross-complementation group 6 antikoerper, DNA excision repair protein ERCC-6 antikoerper, ERCC6 antikoerper, Ercc6 antikoerper, ercc6 antikoerper, LOC100719487 antikoerper

Hintergrund: DNA excision repair protein ERCC-6 (also CS-B protein) is a protein that in humans is encoded by the ERCC6 gene. This gene encodes a DNA-binding protein that is important in transcription-coupled excision repair. The encoded protein has ATP-stimulated ATPase activity, interacts with several transcription and excision repair proteins, and may promote complex formation at DNA repair sites. Mutations in this gene are associated with Cockayne syndrome type B and cerebrooculofacioskeletal syndrome 1. Alternative splicing occurs between a splice site from exon 5 of this gene to the 3' splice site upstream of the open reading frame (ORF) of the adjacent gene, piggyback-derived-3, which activates the alternative polyadenylation site downstream of the piggyback-derived-3 ORF. The resulting transcripts encode a fusion protein that shares sequence with the product of each individual gene.

UniProt: Q03468

Pathways: DNA Reparatur, Chromatin Binding