MEK1 Antikörper (pSer222, pSer226)
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- Target Alle MEK1 (MAP2K1) Antikörper anzeigen
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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Bindungsspezifität
- pSer222, pSer226
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MEK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Produktmerkmale
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Synonyms: mouse anti-MEK1 pS222/MEK2 pS226 Antibody, MAP2K, MEK, MEK1, MKK1, PRKMK1, MEK-1 Antibody, MAP2K2 MEK2, MKK2, PRKMK2, CFC4, MEK-2 Antibody, MEK1 and MEK2 antibody, phosphor MEK1/2
Background: MEK1 pS222/MEK2 pS226 antibody detects MEK1 and MEK2. Mitogen-activated protein kinase kinase 1, (also known as MKK or MEK1), and Mitogen-activated protein kinase kinase 2, (also known as MEK2 or MKK2), are integral components of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 and 2 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. The MEK1 antibody is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
Gene Name: MAP2K1/MAP2K2
- Aufreinigung
- This protein A purified mouse monoclonal antibody specifically binds to the human MEK1 pS222 and MEK2 pS226 phosphorylated sites. Anti-MEK1 pS222/MEK2 pS226 is purified from tissue culture supernatant by protein A purification. Cross reactivity is expected to occur with human, mouse, and rat based on sequence identity of the peptide immunogen.
- Immunogen
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Immunogen: Anti-MEK1 pS222/MEK2 pS226 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues surrounding the S222-226 phosphorylation site conjugated to KLH.
Immunogen Type: Peptide
- Klon
- 17C9-E1-H2-D7-H7-D5
- Isotyp
- IgG
- Top Product
- Discover our top product MAP2K1 Primärantikörper
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- Applikationshinweise
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Application Note: Anti-MEK1 pS222/MEK2 pS226 (MOUSE) antibody is suitable for use in Western Blotting. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 43.5 kDa.
Western Blot Dilution: 1 μg/mL
ELISA Dilution: 1:40,000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.0 mg/mL
- Buffer
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: None
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Haltbarkeit
- 12 months
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- Target
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
- Andere Bezeichnung
- MEK1 (MAP2K1 Produkte)
- Synonyme
- Mek1 antikoerper, CFC3 antikoerper, MAPKK1 antikoerper, MEK1 antikoerper, MKK1 antikoerper, PRKMK1 antikoerper, MEKK1 antikoerper, Prkmk1 antikoerper, mek-2 antikoerper, si:ch211-242m18.2 antikoerper, wu:fj56a12 antikoerper, wu:fj61b01 antikoerper, zgc:56557 antikoerper, ATMEK1 antikoerper, F20B18.180 antikoerper, F20B18_180 antikoerper, MAP kinase/ ERK kinase 1 antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE antikoerper, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 antikoerper, NMAPKK antikoerper, MEK antikoerper, mitogen activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 antikoerper, mitogen-activated protein kinase kinase 1 L homeolog antikoerper, MAP kinase/ ERK kinase 1 antikoerper, Map2k1 antikoerper, MAP2K1 antikoerper, map2k1.L antikoerper, map2k1 antikoerper, MEK1 antikoerper
- UniProt
- Q02750
- Pathways
- MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagie, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
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