REST Antikörper

Produktnummer ABIN5706085

Produktdetails anti-REST Antikörper

Target: REST (RE1-Silencing Transcription Factor (REST))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser REST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Immunogen: RE1-silencing transcription factor

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu REST

Target: REST (RE1-Silencing Transcription Factor (REST))

Andere Bezeichnung: REST (REST Produkte)

Synonyme: NRSF antikoerper, XBR antikoerper, 2610008J04Rik antikoerper, AA407358 antikoerper, xbr antikoerper, nrsf antikoerper, rest antikoerper, resta antikoerper, REST antikoerper, RE1 silencing transcription factor antikoerper, RE1-silencing transcription factor antikoerper, RE1-silencing transcription factor S homeolog antikoerper, REST antikoerper, Rest antikoerper, rest.S antikoerper, rest antikoerper, LOC615792 antikoerper

Hintergrund: Synonyms:NRSF, REST, X2 box repressor, XBR Background:Transcriptional repressor which binds neuron-restrictive silencer element(NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. Transcriptional repression by REST-CDYL via the recruitment of histone methyltransferase EHMT2 may be important in transformation suppression.

Gen-ID: 5978

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity