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REST Antikörper (AA 542-570)

REST Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB36730 unconjugated
Produktnummer ABIN1538486
  • Target Alle REST Antikörper anzeigen
    REST (RE1-Silencing Transcription Factor (REST))
    Bindungsspezifität
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 542-570
    Reaktivität
    • 48
    • 10
    • 8
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 1
    • 1
    Kaninchen
    Klonalität
    • 46
    • 2
    Polyklonal
    Konjugat
    • 26
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser REST Antikörper ist unkonjugiert
    Applikation
    • 32
    • 23
    • 10
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This REST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-570 amino acids from the Central region of human REST.
    Klon
    RB36730
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:2000. WB: 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    REST Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    REST (RE1-Silencing Transcription Factor (REST))
    Andere Bezeichnung
    REST (REST Produkte)
    Synonyme
    NRSF antikoerper, XBR antikoerper, 2610008J04Rik antikoerper, AA407358 antikoerper, xbr antikoerper, nrsf antikoerper, rest antikoerper, resta antikoerper, REST antikoerper, RE1 silencing transcription factor antikoerper, RE1-silencing transcription factor antikoerper, RE1-silencing transcription factor S homeolog antikoerper, REST antikoerper, Rest antikoerper, rest.S antikoerper, rest antikoerper, LOC615792 antikoerper
    Hintergrund
    Transcriptional repressor which binds neuron-restrictive silencer element (NRSE) and represses neuronal gene transcription in non-neuronal cells. Restricts the expression of neuronal genes by associating with two distinct corepressors, mSin3 and CoREST, which in turn recruit histone deacetylase to the promoters of REST-regulated genes. Mediates repression by recruiting the BHC complex at RE1/NRSE sites which acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier.
    Molekulargewicht
    121872
    Gen-ID
    5978
    NCBI Accession
    NP_001180437, NP_005603
    UniProt
    Q13127
    Pathways
    Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity
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