TRIAP1 Antikörper

Produktnummer ABIN5705911

Produktdetails anti-TRIAP1 Antikörper

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIAP1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Immunogen: TP53 regulated inhibitor of apoptosis 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB:1:500-1:5000

Kommentare:

Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with 15351-1-AP( TRIAP1 Antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu TRIAP1

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Andere Bezeichnung: TRIAP1 (TRIAP1 Produkte)

Synonyme: MDM35 antikoerper, P53CSV antikoerper, WF-1 antikoerper, 1810015M01Rik antikoerper, AU020874 antikoerper, AU043831 antikoerper, P53csv antikoerper, Wf-1 antikoerper, p53csv-A antikoerper, triap1 antikoerper, triap1a antikoerper, p53csv-B antikoerper, triap1-a antikoerper, triap1-b antikoerper, triap1b antikoerper, zgc:112025 antikoerper, TP53 regulated inhibitor of apoptosis 1 antikoerper, TP53 regulated inhibitor of apoptosis 1 S homeolog antikoerper, TP53 regulated inhibitor of apoptosis 1 L homeolog antikoerper, TRIAP1 antikoerper, Triap1 antikoerper, triap1.S antikoerper, triap1.L antikoerper, triap1 antikoerper

Hintergrund: Synonyms:15E1.1, HSPC132, P53CSV, Protein 15E1.1, TRIAP1, WF 1 Background:Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).

Molekulargewicht: 32kDa

Gen-ID: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling