TRIAP1 Antikörper (AA 1-76)

Produktnummer ABIN6149492

Der Kaninchen Polyklonal anti-TRIAP1 Antikörper wird verwendet zum Nachweis von TRIAP1 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für TRIAP1 Antikörper (AA 1-76) (ABIN6149492)

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-TRIAP1 Antikörper

Bindungsspezifität: AA 1-76

Sequenz: MNSVGEACTD MKREYDQCFN RWFAEKFLKG DSSGDPCTDL FKRYQQCVQK AIKEKEIPIE GLEFMGHGKE KPENSS

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-76 of human TRIAP1 (NP_057483.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TRIAP1

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Andere Bezeichnung: TRIAP1

Hintergrund: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA between liposomes (in vitro and probably functions as a PA transporter across the mitochondrion intermembrane space (in vivo. Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis.,TRIAP1,HSPC132,MDM35,P53CSV,WF-1,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Mitochondrial metabolism,TRIAP1

Molekulargewicht: 8 kDa

Gen-ID: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling