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PIF1 Antikörper

PIF1 Reaktivität: Human, Maus, Ratte ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5705714
  • Target Alle PIF1 Antikörper anzeigen
    PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
    Reaktivität
    Human, Maus, Ratte
    Wirt
    • 14
    Kaninchen
    Klonalität
    • 14
    Polyklonal
    Konjugat
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIF1 Antikörper ist unkonjugiert
    Applikation
    • 7
    • 3
    • 2
    ELISA, Western Blotting (WB)
    Immunogen
    PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
    Isotyp
    IgG
    Top Product
    Discover our top product PIF1 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze / thaw cycles.
    Lagerung
    -20 °C
    Haltbarkeit
    12 months
  • Target
    PIF1 (PIF1 5'-To-3' DNA Helicase (PIF1))
    Andere Bezeichnung
    PIF1 (PIF1 Produkte)
    Synonyme
    C15orf20 antikoerper, PIF antikoerper, 4631410M14 antikoerper, AI449441 antikoerper, cb934 antikoerper, fe11d03 antikoerper, wu:fe11d03 antikoerper, zgc:56161 antikoerper, PIF1 5'-to-3' DNA helicase antikoerper, PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) antikoerper, PIF1 antikoerper, Pif1 antikoerper, pif1.L antikoerper, pif1 antikoerper
    Hintergrund
    Synonyms:C15orf20 Background:DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex(G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks(DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity.
    Gen-ID
    80119
    UniProt
    Q9H611
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