SYTL2 Antikörper

Produktnummer ABIN5704772

Produktdetails anti-SYTL2 Antikörper

Target: SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SYTL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Immunogen: synaptotagmin-like 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab08460(SYTL2 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu SYTL2

Target: SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))

Andere Bezeichnung: SYTL2 (SYTL2 Produkte)

Synonyme: AI266830 antikoerper, Slp2 antikoerper, Slp2-a antikoerper, Slp2-b antikoerper, Slp2-c antikoerper, Slp2-d antikoerper, mKIAA1597 antikoerper, CHR11SYT antikoerper, EXO4 antikoerper, SGA72M antikoerper, SLP2 antikoerper, SLP2A antikoerper, synaptotagmin-like 2 antikoerper, synaptotagmin like 2 antikoerper, Sytl2 antikoerper, SYTL2 antikoerper

Hintergrund: Synonyms:KIAA1597, SGA72M, SLP2, SLP2A Background:Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine(PS) and phosphatidylinositol-4,5-bisphosphate(PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.

Gen-ID: 54843

UniProt: Q9HCH5