SYTL2 Antikörper
Kurzübersicht für SYTL2 Antikörper (ABIN7075797)
Target
Alle SYTL2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse SYTL2/SLP2
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Applikationshinweise
- IHC/IF (H,M,R) 1:800-1:1600/1:600-1:1200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- SYTL2 (Synaptotagmin Like Protein 2 (SYTL2))
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Andere Bezeichnung
- SYTL2/SLP2
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Hintergrund
- Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive.
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Gen-ID
- 83671
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NCBI Accession
- NP_001035174
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UniProt
- Q99N50
Target
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