MAFB Antikörper

Produktnummer ABIN5704540

Produktdetails anti-MAFB Antikörper

Target: MAFB (Transcription Factor MafB (MAFB))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MAFB

Target: MAFB (Transcription Factor MafB (MAFB))

Andere Bezeichnung: MAFB (MAFB Produkte)

Synonyme: MAFB antikoerper, krml antikoerper, Maf-B antikoerper, XMafB antikoerper, kreisler antikoerper, MGC108453 antikoerper, valentino antikoerper, KRML antikoerper, MCTO antikoerper, Krml antikoerper, b-maf antikoerper, kr antikoerper, mafb antikoerper, val antikoerper, wu:fc22d11 antikoerper, wu:fj82a09 antikoerper, Kreisler antikoerper, Krml1 antikoerper, MAF bZIP transcription factor B antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B S homeolog antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) antikoerper, MAFB antikoerper, mafb antikoerper, mafb.S antikoerper, Mafb antikoerper, mafba antikoerper

Hintergrund: Synonyms:KRML Background:Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, osteoclast, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter(By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

Molekulargewicht: 45 kDa

Gen-ID: 9935

UniProt: Q9Y5Q3