IFIT1 Antikörper

Produktnummer ABIN5703871

Produktdetails anti-IFIT1 Antikörper

Target: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFIT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: interferon-induced protein with tetratricopeptide repeats 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

U-937 cells were subjected to SDS PAGE followed by western blot with FNab04135( IFIT1 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu IFIT1

Target: IFIT1 (Interferon-Induced Protein with Tetratricopeptide Repeats 1 (IFIT1))

Andere Bezeichnung: IFIT1 (IFIT1 Produkte)

Synonyme: C56 antikoerper, G10P1 antikoerper, IFI-56 antikoerper, IFI-56K antikoerper, IFI56 antikoerper, IFIT-1 antikoerper, IFNAI1 antikoerper, ISG56 antikoerper, P56 antikoerper, RNM561 antikoerper, Ifi56 antikoerper, Garg16 antikoerper, DKFZp469C2331 antikoerper, interferon induced protein with tetratricopeptide repeats 1 antikoerper, interferon-induced protein with tetratricopeptide repeats 1 antikoerper, IFIT1 antikoerper, Ifit1 antikoerper, LOC488947 antikoerper, ifit1 antikoerper, LOC100058990 antikoerper, LOC100139670 antikoerper, LOC100475782 antikoerper

Hintergrund: Synonyms:G10P1, GARG 16, IFI 56, IFI 56K, IFI56, IFIT 1, IFIT1, IFNAI1, ISG56, RNM561 Background:Interferon-induced antiviral RNA-binding protein that specifically binds single-stranded RNA bearing a 5'-triphosphate group(PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs and inhibiting expression of viral messenger RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Exhibits antiviral activity against several viruses including human papilloma and hepatitis C viruses.

Molekulargewicht: 55 Kda

Gen-ID: 3434

UniProt: P09914

Pathways: Hepatitis C