IFIT2 Antikörper
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- Target Alle IFIT2 Antikörper anzeigen
- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IFIT2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Immunogen
- interferon-induced protein with tetratricopeptide repeats 2
- Isotyp
- IgG
- Top Product
- Discover our top product IFIT2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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A431 cells were subjected to SDS PAGE followed by western blot with FNab04137( IFIT2 Antibody) at dilution of 1:300
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))
- Andere Bezeichnung
- IFIT2 (IFIT2 Produkte)
- Synonyme
- G10P2 antikoerper, GARG-39 antikoerper, IFI-54 antikoerper, IFI-54K antikoerper, IFI54 antikoerper, IFIT-2 antikoerper, ISG-54 K antikoerper, ISG-54K antikoerper, ISG54 antikoerper, P54 antikoerper, cig42 antikoerper, wu:fb58d07 antikoerper, DKFZp468G198 antikoerper, AV302338 antikoerper, Ifi54 antikoerper, interferon induced protein with tetratricopeptide repeats 2 antikoerper, interferon-induced protein with tetratricopeptide repeats 2 antikoerper, interferon-induced protein with tetratricopeptide repeats 15 antikoerper, IFIT2 antikoerper, Ifit2 antikoerper, ifit15 antikoerper
- Hintergrund
- Synonyms:cig42, G10P2, GARG 39, IFI 54, IFI 54K, IFI54, IFIT 2, IFIT2, ISG 54 K, ISG 54K, ISG54 Background:IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation(cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.
- Molekulargewicht
- 50-55 kDa
- Gen-ID
- 3433
- UniProt
- P09913
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