IFIT2 Antikörper (Internal Region)

Produktnummer ABIN6262455

Produktdetails anti-IFIT2 Antikörper

Target: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Bindungsspezifität: Internal Region

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFIT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: IFIT2 Antibody detects endogenous levels of total IFIT2.

Homologie: Pig

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human IFIT2, corresponding to a region within the internal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu IFIT2

Target: IFIT2 (Interferon-Induced Protein with Tetratricopeptide Repeats 2 (IFIT2))

Andere Bezeichnung: IFIT2 (IFIT2 Produkte)

Synonyme: G10P2 antikoerper, GARG-39 antikoerper, IFI-54 antikoerper, IFI-54K antikoerper, IFI54 antikoerper, IFIT-2 antikoerper, ISG-54 K antikoerper, ISG-54K antikoerper, ISG54 antikoerper, P54 antikoerper, cig42 antikoerper, wu:fb58d07 antikoerper, DKFZp468G198 antikoerper, AV302338 antikoerper, Ifi54 antikoerper, interferon induced protein with tetratricopeptide repeats 2 antikoerper, interferon-induced protein with tetratricopeptide repeats 2 antikoerper, interferon-induced protein with tetratricopeptide repeats 15 antikoerper, IFIT2 antikoerper, Ifit2 antikoerper, ifit15 antikoerper

Hintergrund:

Description: IFN-induced antiviral protein which inhibits expression of viral messenger RNAs lacking 2'-O-methylation of the 5' cap. The ribose 2'-O-methylation would provide a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Viruses evolved several ways to evade this restriction system such as encoding their own 2'-O-methylase for their mRNAs or by stealing host cap containing the 2'-O-methylation (cap snatching mechanism). Binds AU-rich viral RNAs, with or without 5' triphosphorylation, RNA-binding is required for antiviral activity. Can promote apoptosis.

Gene: IFIT2

Molekulargewicht: 55kDa

Gen-ID: 3433

UniProt: P09913