SGK3 Antikörper

Produktnummer ABIN5703403

Produktdetails anti-SGK3 Antikörper

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Immunogen: serum/glucocorticoid regulated kinase family, member 3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab07808(SGK3 antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu SGK3

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Andere Bezeichnung: SGK3 (SGK3 Produkte)

Synonyme: CISK antikoerper, SGK2 antikoerper, SGKL antikoerper, 2510015P22Rik antikoerper, A330005P07Rik antikoerper, Cisk antikoerper, fy antikoerper, fz antikoerper, Sgkl antikoerper, zgc:162253 antikoerper, serum/glucocorticoid regulated kinase family member 3 antikoerper, serum/glucocorticoid regulated kinase 3 antikoerper, serum/glucocorticoid regulated kinase family, member 3 antikoerper, serine/threonine-protein kinase Sgk3 antikoerper, SGK3 antikoerper, Sgk3 antikoerper, LOC464217 antikoerper, sgk3 antikoerper, LOC100231693 antikoerper, LOC100343709 antikoerper, LOC100052030 antikoerper, LOC100521447 antikoerper

Hintergrund: Synonyms:CISK, SGKL Background:Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.

Gen-ID: 23678

UniProt: Q96BR1