SGK3 Antikörper (AA 40-90)

Produktnummer ABIN1387590

Produktdetails anti-SGK3 Antikörper

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Bindungsspezifität: AA 40-90

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SGK3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SGK3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu SGK3

Target: SGK3 (serum/glucocorticoid Regulated Kinase Family, Member 3 (SGK3))

Andere Bezeichnung: SGK3 (SGK3 Produkte)

Synonyme: CISK antikoerper, SGK2 antikoerper, SGKL antikoerper, 2510015P22Rik antikoerper, A330005P07Rik antikoerper, Cisk antikoerper, fy antikoerper, fz antikoerper, Sgkl antikoerper, zgc:162253 antikoerper, serum/glucocorticoid regulated kinase family member 3 antikoerper, serum/glucocorticoid regulated kinase 3 antikoerper, serum/glucocorticoid regulated kinase family, member 3 antikoerper, serine/threonine-protein kinase Sgk3 antikoerper, SGK3 antikoerper, Sgk3 antikoerper, LOC464217 antikoerper, sgk3 antikoerper, LOC100231693 antikoerper, LOC100343709 antikoerper, LOC100052030 antikoerper, LOC100521447 antikoerper

Hintergrund:

Synonyms: CISK, SGK2, SGKL, Serine/threonine-protein kinase Sgk3, Cytokine-independent survival kinase, Serum/glucocorticoid-regulated kinase 3, Serum/glucocorticoid-regulated kinase-like, SGK3

Background: Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, proliferation, survival and migration. Up-regulates Na(+) channels: SCNN1A/ENAC and SCN5A, K(+) channels: KCNA3/KV1.3, KCNE1, KCNQ1 and KCNH2/HERG, epithelial Ca(2+) channels: TRPV5 and TRPV6, chloride channel: BSND, creatine transporter: SLC6A8, Na(+)/dicarboxylate cotransporter: SLC13A2/NADC1, Na(+)-dependent phosphate cotransporter: SLC34A2/NAPI-2B, amino acid transporters: SLC1A5/ASCT2 and SLC6A19, glutamate transporters: SLC1A3/EAAT1, SLC1A6/EAAT4 and SLC1A7/EAAT5, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase. Plays a role in the regulation of renal tubular phosphate transport and bone density. Phosphorylates NEDD4L and GSK3B. Positively regulates ER transcription activity through phosphorylation of FLII. Negatively regulates the function of ITCH/AIP4 via its phosphorylation and thereby prevents CXCR4 from being efficiently sorted to lysosomes.

Gen-ID: 23678

UniProt: Q96BR1