HNRNPC Antikörper
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- Target Alle HNRNPC Antikörper anzeigen
- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
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Reaktivität
- Human, Ratte, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HNRNPC Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Immunogen
- heterogeneous nuclear ribonucleoprotein C (C1/C2)
- Isotyp
- IgG
- Top Product
- Discover our top product HNRNPC Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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HeLa cells were subjected to SDS PAGE followed by western blot with FNab03949(HNRNPC antibody) at dilution of 1:500
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))
- Andere Bezeichnung
- HNRNPC (HNRNPC Produkte)
- Synonyme
- C1 antikoerper, C2 antikoerper, HNRNP antikoerper, HNRPC antikoerper, SNRPC antikoerper, MGC53243 antikoerper, HNRNPC antikoerper, bZ1G18.4 antikoerper, fb57h12 antikoerper, fi16b11 antikoerper, wu:fb57h12 antikoerper, wu:fi16b11 antikoerper, zgc:55701 antikoerper, AL022939 antikoerper, D14Wsu171e antikoerper, Hnrpc antikoerper, Hnrpc1 antikoerper, Hnrpc2 antikoerper, hnRNPC1 antikoerper, hnRNPC2 antikoerper, hnrnp-C antikoerper, hnRNP C antikoerper, hnrnp antikoerper, hnrpc antikoerper, snrpc antikoerper, heterogeneous nuclear ribonucleoprotein C (C1/C2) antikoerper, heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog antikoerper, heterogeneous nuclear ribonucleoprotein C antikoerper, heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog antikoerper, HNRNPC antikoerper, hnrnpc.S antikoerper, hnrnpc antikoerper, Hnrnpc antikoerper, hnrnpc.L antikoerper
- Hintergrund
- Synonyms:HNRPC Background:Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles(PubMed:8264621). Specifically recognizes and binds N6-methyladenosine(m6A)-containing RNAs, a modification present at internal sites of mRNAs that affects mRNA splicing, processing and stability. M6A alters the local structure in mRNAs and long non-coding RNAs(lncRNAs) via a mechanism named 'm(6)A-switch' to facilitate binding of HNRNPC, leading to regulation of mRNA splicing(PubMed:25719671). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides. May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules(PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621).
- Molekulargewicht
- 32 kDa
- Gen-ID
- 3183
- UniProt
- P07910
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