Rekombinanter HNRNPC Antikörper

Produktnummer ABIN7127547

Produktdetails anti-HNRNPC Antikörper

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser HNRNPC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Kreuzreaktivität: Human

Aufreinigung: Affinity-chromatography

Immunogen: A synthesized peptide derived from human HNRNPC

Klon: 9G1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu HNRNPC

Target: HNRNPC (Heterogeneous Nuclear Ribonucleoprotein C (C1/C2) (HNRNPC))

Andere Bezeichnung: HNRNPC (HNRNPC Produkte)

Synonyme: C1 antikoerper, C2 antikoerper, HNRNP antikoerper, HNRPC antikoerper, SNRPC antikoerper, MGC53243 antikoerper, HNRNPC antikoerper, bZ1G18.4 antikoerper, fb57h12 antikoerper, fi16b11 antikoerper, wu:fb57h12 antikoerper, wu:fi16b11 antikoerper, zgc:55701 antikoerper, AL022939 antikoerper, D14Wsu171e antikoerper, Hnrpc antikoerper, Hnrpc1 antikoerper, Hnrpc2 antikoerper, hnRNPC1 antikoerper, hnRNPC2 antikoerper, hnrnp-C antikoerper, hnRNP C antikoerper, hnrnp antikoerper, hnrpc antikoerper, snrpc antikoerper, heterogeneous nuclear ribonucleoprotein C (C1/C2) antikoerper, heterogeneous nuclear ribonucleoprotein C (C1/C2) S homeolog antikoerper, heterogeneous nuclear ribonucleoprotein C antikoerper, heterogeneous nuclear ribonucleoprotein C (C1/C2) L homeolog antikoerper, HNRNPC antikoerper, hnrnpc.S antikoerper, hnrnpc antikoerper, Hnrnpc antikoerper, hnrnpc.L antikoerper

Hintergrund:

Background: Binds pre-mRNA and nucleates the assembly of 40S hnRNP particles (PubMed:8264621). Interacts with poly-U tracts in the 3'-UTR or 5'-UTR of mRNA and modulates the stability and the level of translation of bound mRNA molecules (PubMed:12509468, PubMed:16010978, PubMed:7567451, PubMed:8264621). Single HNRNPC tetramers bind 230-240 nucleotides. Trimers of HNRNPC tetramers bind 700 nucleotides (PubMed:8264621). May play a role in the early steps of spliceosome assembly and pre-mRNA splicing. N6-methyladenosine (m6A) has been shown to alter the local structure in mRNAs and long non-coding RNAs (lncRNAs) via a mechanism named 'm(6)A-switch', facilitating binding of HNRNPC, leading to regulation of mRNA splicing (PubMed:25719671).

Aliases: Heterogeneous nuclear ribonucleoproteins C1/C2, hnRNP C1/C2, HNRNPC, HNRPC

UniProt: P07910