FER Antikörper
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- Target Alle FER Antikörper anzeigen
- FER (FER Tyrosine Kinase (FER))
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FER Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Immunogen
- fer (fps/fes related) tyrosine kinase
- Isotyp
- IgG
- Top Product
- Discover our top product FER Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
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NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab03076( FER Antibody) at dilution of 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- FER (FER Tyrosine Kinase (FER))
- Andere Bezeichnung
- FER (FER Produkte)
- Synonyme
- FerT antikoerper, PPP1R74 antikoerper, TYK3 antikoerper, Fer antikoerper, Flk antikoerper, Flk_retired antikoerper, AV082135 antikoerper, C330004K01Rik antikoerper, Fert antikoerper, FER tyrosine kinase antikoerper, fer (fms/fps related) protein kinase antikoerper, FER antikoerper, Fer antikoerper
- Hintergrund
- Synonyms:TYK3 Background:Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1(high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide(LPS). Plays a role in synapse organization, trafficking of synaptic vesicles, the generation of excitatory postsynaptic currents and neuron-neuron synaptic transmission. Plays a role in neuronal cell death after brain damage. Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3, but the biological relevance of this depends on cell type and stimulus.
- Molekulargewicht
- 95 kDa
- Gen-ID
- 2241
- UniProt
- P16591
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