USP19 Antikörper
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- Target Alle USP19 Antikörper anzeigen
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser USP19 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Immunogen
- ubiquitin specific peptidase 19
- Isotyp
- IgG
- Top Product
- Discover our top product USP19 Primärantikörper
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- Applikationshinweise
- WB : 1:200-1:2000,IP:1:200-1:2000
- Kommentare
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Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09314( USP19 Antibody) at dilution of 1:600
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- Andere Bezeichnung
- USP19 (USP19 Produkte)
- Synonyme
- wu:fc26a05 antikoerper, si:dkey-32e6.9 antikoerper, USP19 antikoerper, MGC145127 antikoerper, ZMYND9 antikoerper, 8430421I07Rik antikoerper, AI047774 antikoerper, Zmynd9 antikoerper, ubiquitin specific peptidase 19 antikoerper, universal stress protein antikoerper, ubiquitin carboxyl-terminal hydrolase 19 antikoerper, usp19 antikoerper, USP19 antikoerper, RR_RS18085 antikoerper, PTRG_09611 antikoerper, Usp19 antikoerper
- Hintergrund
- Synonyms:Deubiquitinating enzyme 19, KIAA0891, Ubiquitin thiolesterase 19, USP19, ZMYND9 Background:Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation(ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol(E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
- Molekulargewicht
- 43kDa,Observed 70kDa,43kDa
- Gen-ID
- 10869
- UniProt
- O94966
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