USP19 Antikörper

Produktnummer ABIN5701384

Produktdetails anti-USP19 Antikörper

Target: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser USP19 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: ubiquitin specific peptidase 19

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000,IP:1:200-1:2000

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09314( USP19 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu USP19

Target: USP19 (Ubiquitin Specific Peptidase 19 (USP19))

Andere Bezeichnung: USP19 (USP19 Produkte)

Synonyme: wu:fc26a05 antikoerper, si:dkey-32e6.9 antikoerper, USP19 antikoerper, MGC145127 antikoerper, ZMYND9 antikoerper, 8430421I07Rik antikoerper, AI047774 antikoerper, Zmynd9 antikoerper, ubiquitin specific peptidase 19 antikoerper, universal stress protein antikoerper, ubiquitin carboxyl-terminal hydrolase 19 antikoerper, usp19 antikoerper, USP19 antikoerper, RR_RS18085 antikoerper, PTRG_09611 antikoerper, Usp19 antikoerper

Hintergrund: Synonyms:Deubiquitinating enzyme 19, KIAA0891, Ubiquitin thiolesterase 19, USP19, ZMYND9 Background:Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation(ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol(E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.

Molekulargewicht: 43kDa,Observed 70kDa,43kDa

Gen-ID: 10869

UniProt: O94966