IL12B Antikörper
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- Target Alle IL12B Antikörper anzeigen
- IL12B (Interleukin 12 beta (IL12B))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser IL12B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Immunogen
- interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Isotyp
- IgG
- Top Product
- Discover our top product IL12B Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
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- Target
- IL12B (Interleukin 12 beta (IL12B))
- Andere Bezeichnung
- IL12B (IL12B Produkte)
- Synonyme
- CLMF antikoerper, CLMF2 antikoerper, IL-12B antikoerper, NKSF antikoerper, NKSF2 antikoerper, p40 antikoerper, Il-12b antikoerper, Il12p40 antikoerper, Il-12p40 antikoerper, Il12 antikoerper, IL-12p40 antikoerper, IL-12 antikoerper, IL-12 p40 antikoerper, il12b antikoerper, il12p40.b antikoerper, zgc:152789 antikoerper, IL-12.p40 antikoerper, IL12p40 antikoerper, IL12B antikoerper, CLMF p40 antikoerper, interleukin 12B antikoerper, interleukin 12b antikoerper, interleukin 12Ba antikoerper, IL12B antikoerper, Il12b antikoerper, il12ba antikoerper
- Hintergrund
- Synonyms:CLMF, CLMF p40, CLMF2, IL 12 subunit p40, IL 12B, IL12B, Interleukin 12 subunit beta, NKSF, NKSF2 Background:Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
- Molekulargewicht
- 37 kDa
- Gen-ID
- 3593
- UniProt
- P29460
- Pathways
- JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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