CDK5RAP3 Antikörper
-
- Target Alle CDK5RAP3 Antikörper anzeigen
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser CDK5RAP3 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
- Immunogen
- CDK5 regulatory subunit associated protein 3
- Isotyp
- IgG
- Top Product
- Discover our top product CDK5RAP3 Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Kommentare
-
HeLa cells were subjected to SDS PAGE followed by western blot with FNab01560(CDK5RAP3 antibody) at dilution of 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze / thaw cycles.
- Lagerung
- -20 °C
- Haltbarkeit
- 12 months
-
- Target
- CDK5RAP3 (CDK5 Regulatory Subunit Associated Protein 3 (CDK5RAP3))
- Andere Bezeichnung
- CDK5RAP3 (CDK5RAP3 Produkte)
- Synonyme
- cdkrap3 antikoerper, fb33h04 antikoerper, fc09c05 antikoerper, id:ibd2920 antikoerper, wu:fb33h04 antikoerper, wu:fc09c05 antikoerper, zgc:86863 antikoerper, CDK5RAP3 antikoerper, cdk5rap3 antikoerper, MGC82350 antikoerper, C53 antikoerper, HSF-27 antikoerper, IC53 antikoerper, LZAP antikoerper, MST016 antikoerper, OK/SW-cl.114 antikoerper, PP1553 antikoerper, 1810007E24Rik antikoerper, BC002318 antikoerper, C81486 antikoerper, CDK5 regulatory subunit associated protein 3 antikoerper, CDK5 regulatory subunit associated protein 3 L homeolog antikoerper, cdk5rap3 antikoerper, CDK5RAP3 antikoerper, cdk5rap3.L antikoerper, Cdk5rap3 antikoerper
- Hintergrund
- Synonyms:IC53, Background:Probable tumor suppressor initially identified as a CDK5R1 interactor controlling cell proliferation(PubMed:12054757, PubMed:12737517). Negatively regulates NF-kappa-B-mediated gene transcription through the control of RELA phosphorylation(PubMed:17785205, PubMed:20228063). Also regulates mitotic G2/M transition checkpoint and mitotic G2 DNA damage checkpoint(PubMed:15790566, PubMed:19223857). Through its interaction with CDKN2A/ARF and MDM2 may induce MDM2-dependent p53/TP53 ubiquitination, stabilization and activation in the nucleus, thereby promoting G1 cell cycle arrest and inhibition of cell proliferation(PubMed:16173922). May play a role in the unfolded protein response, mediating the ufmylation of multiple proteins in response to endoplasmic reticulum stress(PubMed:23152784). May also play a role in the rupture of the nuclear envelope during apoptosis(PubMed:23478299). May regulate MAPK14 activity by regulating its dephosphorylation by PPM1D/WIP1(PubMed:21283629). (Microbial infection) May be negatively regulated by hepatitis B virus large envelope protein mutant pre-s2 to promote mitotic entry.
- Molekulargewicht
- 65 kDa
- Gen-ID
- 80279
- UniProt
- Q96JB5
-