JAML Antikörper

Produktnummer ABIN5697038

Produktdetails anti-JAML Antikörper

Target: JAML (AMICA1) (Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAML Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)

Immunogen: adhesion molecule, interacts with CXADR antigen 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HL-60 cells were subjected to SDS PAGE followed by western blot with FNab04436(AMICA1 antibody) at dilution of 1:800

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu JAML

Target: JAML (AMICA1) (Adhesion Molecule, Interacts with CXADR Antigen 1 (AMICA1))

Andere Bezeichnung: JAML (AMICA1 Produkte)

Synonyme: RGD1562572 antikoerper, AMICA antikoerper, CREA7-1 antikoerper, CREA7-4 antikoerper, Gm638 antikoerper, JAML antikoerper, Crea7 antikoerper, junction adhesion molecule like antikoerper, Jaml antikoerper, JAML antikoerper

Hintergrund: Synonyms:AMICA1 Background:Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. It also controls the transmigration of leukocytes within epithelial and endothelial tissues through adhesive interactions with epithelial and endothelial CXADR.

Molekulargewicht: 30 kDa,44 kDa,50-60 kDa

Gen-ID: 120425

UniProt: Q86YT9