AFF4 Antikörper

Produktnummer ABIN5696887

Produktdetails anti-AFF4 Antikörper

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Immunogen: AF4/FMR2 family, member 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB :1:200-1:2000

Kommentare:

Jurkat cells were subjected to SDS PAGE followed by western blot with FNab00196( AFF4 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Andere Bezeichnung: AFF4 (AFF4 Produkte)

Synonyme: AFF4 antikoerper, RA_m002_jsmFBA6Br antikoerper, AF5Q31 antikoerper, MCEF antikoerper, Alf4 antikoerper, Laf4l antikoerper, AF4/FMR2 family member 4 L homeolog antikoerper, AF4/FMR2 family member 4 antikoerper, AF4/FMR2 family, member 4 antikoerper, aff4.L antikoerper, AFF4 antikoerper, aff4 antikoerper, Aff4 antikoerper

Hintergrund: Synonyms:AF4/FMR2 family member 4, AF4/FMR2 family, member 4, AF5Q31, AFF4, MCEF, Protein AF 5q31 Background:Key component of the super elongation complex(SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins(ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Molekulargewicht: 127kDa,observed 150kDa

Gen-ID: 27125

UniProt: Q9UHB7