AFF4 Antikörper (C-Term)

Produktnummer ABIN6259815

Produktdetails anti-AFF4 Antikörper

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Spezifität: AFF4 Antibody detects endogenous levels of total AFF4.

Homologie: Pig,Bovine,Horse,Sheep,Chicken

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human AFF4, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu AFF4

Target: AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

Andere Bezeichnung: AFF4 (AFF4 Produkte)

Synonyme: AFF4 antikoerper, RA_m002_jsmFBA6Br antikoerper, AF5Q31 antikoerper, MCEF antikoerper, Alf4 antikoerper, Laf4l antikoerper, AF4/FMR2 family member 4 L homeolog antikoerper, AF4/FMR2 family member 4 antikoerper, AF4/FMR2 family, member 4 antikoerper, aff4.L antikoerper, AFF4 antikoerper, aff4 antikoerper, Aff4 antikoerper

Hintergrund:

Description: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

Gene: AFF4

Molekulargewicht: 127kDa

Gen-ID: 27125

UniProt: Q9UHB7