TNFRSF11A Antikörper (AA 34-211)

Produktnummer ABIN5692815

Produktdetails anti-TNFRSF11A Antikörper

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Bindungsspezifität: AA 34-211

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for RANK detection. Tested with WB, Direct ELISA in Human,Rat.

Immunogen: E. coli-derived human RANK recombinant protein (Position: C34-L211).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu TNFRSF11A

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Andere Bezeichnung: TNFRSF11A (TNFRSF11A Produkte)

Synonyme: RANK antikoerper, RGD1563614 antikoerper, TNFRSF11A antikoerper, Ly109 antikoerper, ODFR antikoerper, OFE antikoerper, Rank antikoerper, TRANCE-R antikoerper, mRANK antikoerper, CD265 antikoerper, FEO antikoerper, LOH18CR1 antikoerper, OPTB7 antikoerper, OSTS antikoerper, PDB2 antikoerper, TRANCER antikoerper, TNF receptor superfamily member 11A antikoerper, TNF receptor superfamily member 11a antikoerper, tumor necrosis factor receptor superfamily, member 11a, NFKB activator antikoerper, Tnfrsf11a antikoerper, TNFRSF11A antikoerper

Hintergrund:

Synonyms: Tumor necrosis factor receptor superfamily member 11A, Osteoclast differentiation factor receptor, ODFR, Receptor activator of NF-KB, CD265, TNFRSF11A, RANK

Tissue Specificity: Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.

Background: Receptor Activator of Nuclear Factor κ B (RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. It is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, this gene is mapped to 18q22.1.

UniProt: Q9Y6Q6

Pathways: NF-kappaB Signalweg