PACS2 antibody is human, mouse and rat reactive. At least three isoforms of PACS2 are known to exist, this antibody will detect all three. PACS2 antibody is predicted to not cross-react with PACS1.
Aufreinigung
PACS2 antibody is affinity chromatography purified via peptide column.
Immunogen
PACS2 antibody was raised against a 17 amino acid peptide near the center of human PACS2.
The immunogen is located within amino acids 330 - 380 of PACS2.
PACS2
Reaktivität: Human
ELISA, WB, IHC
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
PACS2 antibody can be used for detection of PACS2 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for immunohistochemistry starting at 5 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PACS2 antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
PACS2 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Target
PACS2
(phosphofurin Acidic Cluster Sorting Protein 2 (PACS2))
PACS2 (phosphofurin acidic cluster sorting protein-2), PACS1L, is an 889 amino acid protein that localizes to both the mitochondrion and the lumen of the endoplasmic reticulum (ER) and belongs to the PACS family (1,2). It is expressed in a broad range of tissues with highest expression in skeletal muscle, brain, heart, testis and pancreas (2,). PACS2 interacts with Polycystin-2 and BID and functions as a sorting protein that regulates mitochondria-ER communication and is thought to be involved in ion channel trafficking, specifically direct cluster-containing ion channels to distinct subcellular compartments (3-5).