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DIS3 Antikörper (AA 90-140)
DIS3
Reaktivität: Human, Maus, Ratte
WB, ELISA, IHC (p), IF
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689945
Produktdetails anti-DIS3 Antikörper
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Target
Alle DIS3 Antikörper anzeigen
DIS3
(Exosome Complex Exonuclease RRP44 (DIS3))
Bindungsspezifität
Alle Epitope für DIS3 Antikörper
AA 90-140
Reaktivität
Alle Reaktivitäten für DIS3 Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für DIS3 Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für DIS3 Antikörper
Polyklonal
Konjugat
Alle Konjugate für DIS3 Antikörper
Dieser DIS3 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für DIS3 Antikörper
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
Spezifität
Multiple isoforms of DIS3 are known to exist.
Aufreinigung
DIS3 Antibody is affinity chromatography purified via peptide column.
Immunogen
DIS3 antibody was raised against an 18 amino acid peptide near the amino terminus of human DIS3. The immunogen is located within amino acids 90 - 140 of DIS3.
Isotyp
IgG
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Anwendungsinformationen
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Applikationshinweise
DIS3 antibody can be used for detection of DIS3 by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
DIS3 Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
DIS3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu DIS3
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Target
DIS3
(Exosome Complex Exonuclease RRP44 (DIS3))
Andere Bezeichnung
DIS3 (DIS3 Produkte )
Synonyme
EXOSC11 antikoerper, KIAA1008 antikoerper, RP11-342J4.3 antikoerper, RRP44 antikoerper, bA555G22.1 antikoerper, dis3p antikoerper, DIS3 antikoerper, 2810028N01Rik antikoerper, RGD1304646 antikoerper, wu:fb08g12 antikoerper, dis3 antikoerper, DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 exosome endoribonuclease and 3'-5' exoribonuclease antikoerper, DIS3 antikoerper, Dis3 antikoerper, dis3 antikoerper, dis3.L antikoerper
Hintergrund
DIS3 Antibody: The exosome is involved in a multitude of cellular RNA processing and degradation events. DIS3, also known as exosome complex exonuclease RRP44, is a ribonuclease that acts directly in the processing, turnover, and surveillance of a large number of distinct RNA species. DIS3 localizes to both the cytoplasm and the nucleus and contains one PINc domain. It is widely expressed with highest expression in testis and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis.
Molekulargewicht
Predicted: 105 kDa Observed: 103 kDa
Gen-ID
22894
NCBI Accession
NP_055768
UniProt
Q9Y2L1
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