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beta-2 Microglobulin Antikörper (C-Term)
B2M
Reaktivität: Human
WB, ELISA, IF, IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktnummer ABIN5689895
Produktdetails anti-beta-2 Microglobulin Antikörper
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Target
Alle beta-2 Microglobulin (B2M) Antikörper anzeigen
beta-2 Microglobulin (B2M)
(beta-2-Microglobulin (B2M))
Bindungsspezifität
Alle Epitope für beta-2 Microglobulin Antikörper
C-Term
Reaktivität
Alle Reaktivitäten für beta-2 Microglobulin Antikörper
Human
Wirt
Alle Wirte für beta-2 Microglobulin Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für beta-2 Microglobulin Antikörper
Polyklonal
Konjugat
Alle Konjugate für beta-2 Microglobulin Antikörper
Dieser beta-2 Microglobulin Antikörper ist unkonjugiert
Applikation
Alle Applikationen für beta-2 Microglobulin Antikörper
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
B2M antibody is human reactive.
Aufreinigung
B2M Antibody is affinity chromatography purified via peptide column.
Immunogen
B2M antibody was raised against a 15 amino acid peptide near the carboxy terminus of human B2M. The immunogen is located within the last 50 amino acids of B2M.
Isotyp
IgG
Top Product
Discover our top product B2M Primärantikörper
Alternativen
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Anwendungsinformationen
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Applikationshinweise
B2M antibody can be used for detection of B2M by Western blot at 1 - 2 μ,g/mL.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Format
Liquid
Konzentration
1 mg/mL
Buffer
B2M Antibody is supplied in PBS containing 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
B2M antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
Details zu beta-2 Microglobulin
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Target
beta-2 Microglobulin (B2M)
(beta-2-Microglobulin (B2M))
Andere Bezeichnung
B2M (B2M Produkte )
Synonyme
Ly-m11 antikoerper, beta2-m antikoerper, beta2m antikoerper, bwm antikoerper, wu:fa94c05 antikoerper, wu:fb10a09 antikoerper, b2m-W01 antikoerper, b2m-W03 antikoerper, b2m-Z01 antikoerper, b2m-Z02 antikoerper, b2m-Z03 antikoerper, B2M antikoerper, b2m antikoerper, B2MG antikoerper, wu:fb66f11 antikoerper, wu:fj01f08 antikoerper, zgc:64161 antikoerper, b-2-m antikoerper, beta-2-microglobulin antikoerper, beta-2 microglobulin antikoerper, beta-2-microglobulin S homeolog antikoerper, beta-2-microglobulin, like antikoerper, B2M antikoerper, B2m antikoerper, b2m antikoerper, b2m.S antikoerper, b2ml antikoerper
Hintergrund
B2M Antibody: Beta2-microglobulin (B2M) is a principal component of the Major Histocompatibility Complex (MHC) class I molecule, a ternary membrane protein complex that displays fragments derived from proteolyzed cytosolic proteins on the surface of cells for recognition by the surveillance immune system (1,2). B2M is involved in the presentation of peptide antigens to the immune system and plays a critically important role in immune system function (3). It is expressed on nearly all nucleated cells and contains one Ig-like C1-type (immunoglobulin-like) domain (2,3). Mutations in the Beta 2-microglobulin gene can enhance the progression of malignant melanoma and osteoarthropathy (4,5).
Molekulargewicht
Predicted: 13 kDa Observed: 12 kDa
Gen-ID
567
NCBI Accession
NP_004039
UniProt
P61769
Pathways
T-Zell Rezeptor Signalweg , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process
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