VASP Antikörper (pSer157)

Produktnummer ABIN5689768

Produktdetails anti-VASP Antikörper

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Bindungsspezifität: pSer157

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VASP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: This antibody detects endogenous level of VASP only when phosphorylated at serine 157.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.

Immunogen: VASP (Phospho-Ser157) antibody was raised against a peptide sequence around phosphorylation site of serine 157 (R-V-S (p) -N-A) derived from Human VASP.

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+),  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu VASP

Target: VASP (Vasodilator-Stimulated phosphoprotein (VASP))

Andere Bezeichnung: VASP (VASP Produkte)

Synonyme: vasp antikoerper, MGC80889 antikoerper, wu:fb23b04 antikoerper, wu:fk84g05 antikoerper, zgc:110347 antikoerper, si:dkey-113g17.1 antikoerper, si:ch211-202c21.1 antikoerper, DDBDRAFT_0188463 antikoerper, DDBDRAFT_0229340 antikoerper, DDB_0188463 antikoerper, DDB_0229340 antikoerper, VASP antikoerper, vasodilator stimulated phosphoprotein S homeolog antikoerper, vasodilator stimulated phosphoprotein b antikoerper, protein enabled antikoerper, vasodilator-stimulated phosphoprotein antikoerper, vasodilator stimulated phosphoprotein a antikoerper, vasodilator stimulated phosphoprotein antikoerper, vasp.S antikoerper, vaspb antikoerper, LOC5573842 antikoerper, CpipJ_CPIJ004706 antikoerper, CpipJ_CPIJ004707 antikoerper, vasP antikoerper, vasp antikoerper, VASP antikoerper, vaspa antikoerper, Vasp antikoerper

Hintergrund: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation.

Molekulargewicht: 50 kDa

Gen-ID: 7408

NCBI Accession: NP_003361

UniProt: P50552

Pathways: T-Zell Rezeptor Signalweg, Regulation of Actin Filament Polymerization, Tube Formation